Why Vitamin C is essential to the human body
Vitamin C is a nutrient that isn’t just construed as influential for its role in the human body but also for the absorption of other vital nutrients that are essential for the body. Healthy tendons, ligaments, and blood vessels are some of the works of vitamin C that exemplify the role of vitamin C as a backer involved in the absorption of calcium and several other amino acids. A long-term absence or scarcity of this essential nutrient in the body could make way for a condition called scurvy. In the worst of the scenarios, vitamin C deficiency could culminate in cancer. It is a sad state of affairs to resemble such facts with the inconvenience caused to the general public due to the lack of awareness. A prompt awareness in this regard can be kept up by keeping a track of the early signs and symptoms of vitamin C deficiency that would undoubtedly relieve the body of any severance that follows.
Premature wrinkling of skin: Optimum levels of Vitamin C are important for the upkeep of your skin’s health. Excess exposure of the skin belonging to any part of the body to UV radiation could fence in harm into the various dermal layers of skin and that can be considered immense enough to be equalized with the harm caused by the free radicals. Even if a person isn’t getting exposed to UV radiation on a regular basis, a distinct change in the pattern of skin could catch a clear eye in the form of enormously thickened dermis. Some people might even notice a distinct form of bruise or bleeding point circumferencing the hair follicles. All this and much more oddly exhilarated changes with regards to the skin can be avoided by maintaining an adequate amount of collagen in subdermal layers. One can bid on vitamin C for synthesizing adequate amounts of collagen that are sizable enough for repairing any damage that might have been induced by either UV radiation or free radicals. So, depletion of collagen stores can be considered as the preliminary marker of vitamin C deficiency.
Hair quality: The quality of hair that grows out of every follicle can be guessed by its growth pattern especially in the case of a person who reeks of Vitamin C deficiency. ‘Corkscrew pattern’ - could serve as a vital clue for anyone who is looking for a marker of vitamin C deficiency at an early stage. Yet another finding that could rule out the absence/presence of vitamin C deficiency could be the thickness of hair. People with vitamin C deficiency can easily notice the amiss nature of hair which is subsequently prompted by their frequent breakage.
Patchy gums: Bleeding points in gums is a sign that is hard to go unnoticed. Vitamin C could be a controller of gum health. The antioxidant action of vitamin C ends to wear off quick when the deficiency of vitamin C has been in the body for quite a while. As a result inflammation sets in which luckily doesn't have anything to combat with. Eventually, the gums give in to the inflammation and start bleeding.
Inability to catch up with the tooth’s upkeep: Vitamin C or ascorbic acid supports a major part of the teeth’s layer named dentine. Dentine is the layer of the tooth that follows enamel. A continual supply of vitamin C to dentine helps in the upkeep of calcium concentrations in the tooth. If there is a chronic absence or deficiency of vitamin C in the body, the calcium levels in the tooth would not be able to suffice the amount of repair required to maintain the tooth in an unaltered state following the daily state of affairs of wear and tear. As a result, the opportunistic bacteria sink their their jaws into the tooth and extend their toxins to the layer of dentin and cause immense decay. The commonest bacteria to evade the dentinal walls of the tooth is staphylococcus aureus.
Extensive bruises: A recent study published by the US National Library of Medicine National Institutes of Health presented a new take on the incidence of bruises. During the aforementioned study, a prompt health care was provided for the bruises with an additional step of vitamin C supplement administration. Following the study, a standard dose of vitamin
C was constrained by the U.S. National Academy of Medicine. A daily uptake of vitamin C recommended for adult men would be of 90 mg while that for the women would be of 75mg. The aforementioned doses have been recommended for non-smoking men and women around the countries. The smokers would be required to consume an additional 35 mg of vitamin C in the form of supplements or in their diet.
Closing in of wounds disrupted : A normal scratch would usually take up a week’s time for closure. Any extra minute spent in their healing would be a call for definite measures. Delay in closure of normal wounds is indicative of restrained amounts of vitamin C in the body. This could be the time for you to choose a supplement that ensures the right amount of vitamin C intake everyday. Disrupted wound closure is one of the key signs of scurvy that tends to get mixed up in the classic signs of any of the clotting disorders (especially when one suffers from it since birth).
Unexplained joint pain: Inflammation of joints becomes a common incidence that can be often witnessed in the cases of scurvy. No later than March 2019, a case was reported at the Chi Mei Hospital in Taiwan. The case belonged to a 56 year old women who reported a constant pain in the metatarsals of her hand that was severe enough to refrain her from using the chopsticks during her meals. While the patient resorted to the obvious means of painkillers to take care of the inflammation, the physicians from the Department of Anesthesia and Pain Management at Chi Mei Hospital in Taiwan prescribed her vitamin C supplements to take care of the underlying cause. A significant improvement in the strength of the metatarsals was witnessed within the expected time frame of 3 weeks. Chili peppers and golden kiwi are one of the richest sources of vitamin C. So if you’ve nailed the daily dose of 100mg then all you have to make sure is about keeping a whole bay off of any of the symptoms that maintain scurvy. Some of the other salad components that can be added to be sure of keeping the expeditious amount of vitamin C going in the body would be the blueberries, papaya, oranges, and kale.
Malaise: Malaise follows the basic condition of either a deficiency or exertion in the body. The foremost sign that can be witnessed in such a scenario would be of the tremendous change that persuades the sleeping pattern. A recent study performed on a couple of youngsters stirred the use of vitamin C as a regime against malaise in most conditions. This study was performed in south korea and during its course it was that confirmed that vitamin C held a firm grasp on oxidative stress. Vitamin C supplements have been of aid in lowering oxidative stress within time frame of two hours when administered through the intravenous route and approx. one day when consumed or administered orally. The route of administration of vitamin C is solely based on the levels of oxidative stress existent in the body at a certain time.
Nail breakage without biting: While the condition of brittle nails is noticeable in several conditions, it can be considered as a secondary symptom in addition to any of the aforementioned markers in a case of scurvy. For instance, biotin or vitamin B7 deficiency is yet another scenario that presents with the sign of brittle nails. To complete the daily dose of vitamin C that is minimally required for maintaining the health status of nails, it is recommended to either add more citrus fruits in the diet or supplements that assure an uptake of 400mg.
Frequent nosebleeds: Healthy blood vessels call for a lot of maintenance when it comes to their linings. Vitamin C plays an essential role in sustaining the high profile activity of blood vessels through some of the major vital organs of the body. Most sensitive of the blood capillaries can be found around the nasal bone. Nosebleeds are a common occurrence in the cases of scurvy. While multivitamin supplements can be used as a prophylactic measure, it is always commendable to opt for the purchase of supplements that concentrate primarily on the supply of vitamin C.
Sepsis can be considered as a vehement, inflammation-inducing response of the body to any infection. Septicemia on the other hand would be a condition that gets formed in the body once the stage of sepsis has gone out of control. Vitamin C is an essential nutrient that might come handy in backing up the action of hydrocortisone. Hydrocortisone is a steroidal preparation that cuddles down the inflammation-inducing response of the body to the infection. Most of the patients who suffer with septicaemia have reported an unstable response of the body and in most cases of the regularly used antibiotics to CO circulation. CO circulation is the circulation of toxic secretions initiated by the bacterial enzymes. A standard treatment regimen for septicaemia would comprise of mannitol, vitamin C (I.v) and hydrocortisone. Clive de Carle (M.D) is a nutrition expert who perfectly explains the unfair and scarce use of vitamin C in the cases of septicemia. According to the concepts followed in the 1960’s, vitamin C was used on a usual basis for the treatment of conditions like cold and flu that might have been initiated by some of the most vicious of viruses. Chronic fatigue syndrome is a deteriorating condition that originates from the shadow of an acquired infection. Similarly, the M.E patients carry infections because they are driven by it. According to Clive de Carle, It is important to improve our own defenses to prevent the very initiation of any infection in the body. The preventive measures taken in this regard would require a special call for the diabetics due to the immunocompromised state of their body. Dr Sarah Myhill supports this practice by explaining the way in which the ground hog chapter works. A ground hog chapter would entail the administration of sufficiently high amounts of vitamin C through the systemic route on a daily basis once the slightest hint of any infection has been experienced by a person. Though the dose of vitamin C for treatment of infection varies on an individual basis, a standard dose 5000 mg for infections has been ruled out as safe and effectual one. This dose is far higher than the regular dose of 30 mg of vitamin C that is recommended for the purpose of just stalling scurvy. Infections can make their way into the body through food and/or air. Most of the microbes get in through the gut and then branch their influence from there. While Dr Sarah Myhill confirms the fact that a sudden and strong dose of vitamin C might trigger a diarrhea in the body she also claims that it worth obscuring over the suffering found in the bed-bound days having a flu. She also quotes that a substantial amount of bias has been shown towards vitamin C supplements when it comes to their use against infections. This partiality can be based on the profit-monitoring mentalities of the professionals in medical line who promote the use of only the breakthrough or mainstream medications that would fetch profits for medical companies worldwide for a really long time. Vitamin C, though effective is still a mere nutrient that might according to the profit-monitoring medical companies lack the face value required to fetch them millions. One of the richest sources of ascorbic acid is fermented corn which makes its use rare in raw form. There are people around the globe who are allergic to corn or in more bitter sense might abstain from the consumption of fermented corn. Although, the corn used for fermentation is non-GMO but that doesn't encourage the corn sensitive patients from trying their hands on it.
Stalling the spread and intensity of septicaemia can be even more essential in the cases that contain some form of cardiac disorder. The role of antibiotics can be considered reliable but only for an insipid matter of time until the system gives up to the resistant strains of bacteria. In the cardiovascular cases, it is as common to expect an incidence of septicemia as a cardiac arrest anytime during the treatment stages. While the route followed by bacteria from septicemia to cardiac arrest still remains unexplained, it is an epoch-making fact that over 20,000 patients undergo the experience of in-hospital cardiac arrest (IHCA) almost every year. The foremost measure taken in this regard by most physicians is of correcting any form metabolic syndrome. Metabolic syndrome is a condition that involves the depletion of antioxidants which could possibly encourage the initiation of any infection in its most cruelest forms. Almost 35% of U.S population falls sick because of the heftiness exhibited by the symptoms of metabolic syndrome. This syndrome could pose as a serious condition when it starts exhibiting the symptoms of cognitive decline and dementia. Metabolic syndrome is a disorder contributed by the chronic consumption of saturated fats that most probably make their way into the body through junk foods. What would be much peculiar to estimate would be the series of diseases that follow chronic metabolic syndrome only to leave the patients on a regime to follow for months or even years. The commonest ones of them would be the fatty liver, diabetes and any of the cardiac issues such as the myocardial infarction. Any patient who has been diagnosed of metabolic syndrome would exhibit the signs of high BP, high-end sugar levels and uncontrolled levels of LDL. The recent publications of Redox Biology suggest that the onset of metabolic syndrome can be reasoned with the deficiency of vitamin C and therefore the essential gut bacteria which makes it impossible for the food stuff to get digested in time. Situation turns tricky only when the antioxidant levels go real low and there isn’t sufficient vitamin C in the body to combat the oxidative stress that follows.
Lipid peroxidation is the process that initiates the release of free radicals in the body. As a result, junk food particles get trapped in the process of degradation instead of digestions as the gut lining gets intruded due to lipid peroxidation. The saddest part is that the intrusion might cause some portions of the gut wall to fall into the digestive juices and therefore the by product. These gut pieces readily enter into the blood’s circulation. Such a derangement in the body’s curriculum would cause the neutrophils to get activated. So, when the immune system gets alarmed, one can be sure of expecting a home invasion that would destroy the body’s own immune system just like it commences in the case of an autoimmune disorder. Yet another development in this regard was mentioned in the Asia Pacific Journal of Clinical Nutrition. According to a recent article in the journal, fish oil was found to be effectual in controlling the mortality rate that accounts for most of the cases of septicemia. One of the most preferable modes of administration of fish oil in the patients of septicaemia would be the intravenous one. A faster recovery can be designed in such a manner along with the administration of hydrocortisone. Some physicians adopt the approach of ‘Prevention is better than Cure’ in many plausible cases of septicemia that are linked with diabetes. In addition to vitamin C, it is suggested to opt for the intake of several other nutrients that could possibly support the immune system in a big way. Some of these micronutrients that promote the production of lysine and proline would be vitamin B6, vitamin B12 and, vitamin E.
FDA is a solitary body in the U.S that controls the circulation of various drugs and supplements in the pharmacies. According to its recent regulation, FDA has denied the use of vitamin C injections. The adjusted reason provided by the FDA to do so is that vitamin C cannot be patented and therefore slackens the approval procedure of the FDA. The the acknowledgement provided by the FDA liquifies the possible line of thought that vitamin C can actually be safe to use. So, in a way patients would be deprived of the skills of vitamin C injections just because FDA follows the monotony of patenting only drugs for intravenous usage. Some of the other intravenous nutrient formulations that have been banned from their manufacture by the FDA are magnesium chloride and injectable vitamin B-complex 100. In their knowledge a synergistic combination of intravenous magnesium chloride, I.v vitamin C and injectable vitamin B-complex 100 was being used personally by patients and health facilities for the treatment of septicaemia and chronic fatigue syndrome.
A latest shred of evidence enlightens us that vitamin C is even capable of controlling the signs of swine flu. ‘Natural Health Worldwide’ is a website created by Dr. Sarah Myhill in this regard. More than a nutrient vitamin C can be considered as a treatment modality in the cases of swine flu. One of the most compelling cases to prove this theory was the one that was reported in the news of March 2016. The news was about a farmer in New zealand who had fallen sick due to the condition of swine flu. It was an advanced case of swine flu that was at the verge of ‘not-making-it’. The patient, Allan smith seemed to have contracted swine flu from the regions of Fiji during his vacation. After his return, he noticed the symptoms indicative of swine flu and reported the same to the nearest health care facility. The grevious attitude of the situation led to inflow of fluids into the lungs of Allan smith. Apparently, one of the Smith’s relatives suggested the intravenous administration of vitamin C. This urgent and cautious step led to a significant improvement in the capacity of lungs within a time frame of 24 hours. A similar dose of IV vitamin C was administered for a period of approx. 2 weeks. What made this news even more controversial was the fact that Allan was diagnosed with leukaemia during his stay at the hospital when he was admitted for swine flu. This case was followed up for a year after the patient’s discharge from the health facility and an assured absence of any signs linked with either swine flu or leukaemia were reported. Vitamin C excels at keeping the flag of immunity up against swine flu in the biggest way possible. As the name suggests, swine flu is a contagious disease that gets transferred from pigs to humans mostly during their visit to a poultry farm. The prime virus involved in this disease is the Influenza A virus. The drug-resistance potential of this virus was one of the causes that led to the pandemic of swine flu in 2009. Primarily, two variants of IAV drugs are used for capturing the toxic potential of influenza A virus - adamantanes and neuraminidase (NA) inhibitors. Since, the aforementioned antibiotics can’t be ruled out for raising resistant strains of Influenza A virus, it is always a safer option to raise the immune levels that would never go haywire when it comes to dealing with the swine flu virus.
When used in a stable form and under the care of a qualified physician, intravenous vitamin C is capable of taking care of the highest degree of burns. A burn injury calls for a constant supply of fluids to the body’s vital organs for resuscitating the vital stats of the patient. As vital organs take on their original form, a stable amount of renal blood flow can be witnessed. Fluid resuscitation is critical and is therefore maintained in a standard manner to avoid the onset of abdominal compartment syndrome. Some of the prominent markers of this syndrome would be pulmonary oedema, and loss of airway control. These symptoms only add to the misery of a burns patient. A high i.v dose of vitamin C loosens the use of fluid resuscitation in a burns injury patient and therefore stalls any chances of an incidence of abdominal compartment syndrome. Intravenous administration of vitamin C is essential in the first 24 hours of the occurrence of a burn injury. Also, the thoughtful and initial use of vitamin C in the intravenous form assures a hefty decrease in the postburn proteins and leakage of fluids. Free radicals do a lot of damage to the body. This is something that can be essentially avoided by a regular intake of vitamin C that thoroughly limits the proceedings of the lipid peroxidation process. There are a dozen trials done in this regard and all of them came out to be true.
ICU (Intensive Care Unit) is an area of the hospital where the patients are shifted when in the most sensitive state of their health. Vitamin C supplements are capable of reducing the extra hours spent in the emergency unit. Administration of Vitamin C in some of the most critical cases of the ICU can be counted as something that goes beyond the dose-response relationship as the selective dose of vitamin C is not just dependent on condition of the patient but also on the body proportions of the patient. Some of prime conditions that would obviously call for an admission to the ICU would be traumatic traffic accidents, burns injury, post-operative cases of a major surgical procedure, and coronary arrest. As most of the theories and studies suggest, vitamin C works through the mechanism of production of amino acids but the exact mechanism of action of vitamin C that flexibly adjusts to the intensity of every form of disease might still be unknown. The plausible statements that have been put forth in this regard support the involvement of vitamin C with the genes and DNA structure. Such statements can be substantiated by the fact that the levels of vitamin C were found to be lesser than normal in many patients who came up with some form of illness or health condition. Several studies that have been based on nationwide databases that comprised of analysis performed on a pool of patients who were admitted in the ICU.
According to the analysis, approx. 1700 patients were able to head home following a speedy recovery after the administration of vitamin C. Three of these trials that were included in this analysis comprised of patients who required mechanical ventilation. After the administration of vitamin C, the duration of mechanical ventilation was found to be submerged by 18%. Post-operative atrial fibrillation is a common condition that follows most patients who have been released from the hospital or the ICU after a surgical procedure. Post-operative atrial fibrillation can be defined as a irregularity in the circadian rhythm of the heart. A prolonged exposure to this condition after an operation might result in a stroke or congestive cardiac failure. Researchers at the University of Helsinki, Finland carried out a trial to affirm the effect of vitamin C on postoperative atrial fibrillation. During the studies, it was concluded that vitamin C was able to reduce the risk of a recurrence of the condition of atrial fibrillation by 87%. Needless to say, the lengths of the hospital stays that followed the operations as a protocol of post-operative care were reduced too. Most of the non-US patients treated during the trials were administered vitamin C orally.