ANSWER: No, There is no evidence to suggest that D-mannose can irritate the bladder.

In fact, some people use D-mannose as a natural remedy for bladder irritation and urinary tract infections (UTIs).

However, it is always best to consult with a healthcare provider before using any natural remedy for a medical condition.

Everyone is different and what works for some people may not work for others. It is important to work with a healthcare provider to develop a treatment plan that is right for you.

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