ANSWER: D-mannose is generally considered safe for most people when taken in appropriate amounts.
It is a naturally-occurring sugar that is found in small quantities in fruits such as cranberries and blueberries. However, as with any supplement, it is important to consult with your healthcare provider before taking D-mannose to ensure it is safe for you and to determine the appropriate dosage.
In rare cases, D-mannose may cause side effects such as bloating, gas, or diarrhea. It is also important to note that D-mannose can interfere with certain medications, such as those used to treat diabetes, so it is important to discuss any supplements you are taking with your healthcare provider.